Delsamax COREThe DelsaMax Core provides sizing of particles as small as 0.4nm with sample volumes as low as 1µl with a separate static light scattering optical system for accurate molecular weight measurement from 300 to 106 Da.
The DelsaMax CORE is a combination Dynamic Light Scattering (DLS) and Static Light Scattering (SLS) instrument. The DLS detector operates at 90 degrees to measure the size distribution of the hydrodynamics radius, whereas the independent SLS detector, which also operates at 90 degrees, can measure the molecular weight of small molecules.
DelsaMax CORE can be used for a broad range of applications requiring both accuracy and high sensitivity. For example, the DelsaMax CORE is ideally suited for studies of nanoparticles, proteins, vesicles, viruses, and colloids.
The sample is filtered to eliminate dust particles, which might interfere with the signal from the molecules being measured. Solutions are injected into cuvettes and placed into the sample cell. The total sample injection volume (including filtration) is approximately 20 µl using the 10 µl cuvette. After the cuvette is placed in the sample cell, the sample is illuminated by the laser. The scattered light is correlated in the DelsaMax CORE, which then sends the results to the PC for analysis by the DelsaMax Software software package.
ApplicationsThe DelsaMax CORE can be used for many different applications.
Using the DelsaMax CORE for Molecular Weight Analysis – Protein Sizing Application Note
DelsaMax CORE – Exosome Purification and Characterisation Application Note
Beckman Coulter Instruments – Liposome Characterisation Application Note