Particle Size: An Important Factor in Many Applications
Particle size is the physical property that describes the size of individual particles in a material. It is an important factor in many applications and industries, ranging from pharmaceuticals, cosmetics, and food production to chemical processing and construction. In this blog post, we will dive into the importance of particle size and how it can […]
UK Demo unit of the BioLector XT Microbioreactor installed at Meritics Ltd
Setting up the BioLector XT Microbioreactor We were delighted to welcome Sophia Lorke, Field Application Specialist from Beckman Coulter Life Sciences to Meritics for the installation and training on the BioLector XT Microbioreactor. Meritics are proud to partner with Beckman Coulter Life Sciences by hosting the UK demonstration unit of the BioLector XT Microbioreactor at […]
Monitoring Yeast Cultures with the BioLector XT and Multisizer 4e instruments
Yeasts are unicellular fungi that share cellular structures and processes that are highly conserved amongst eukaryotes (e.g., membrane-bound organelles, a cytoskeleton, nuclear DNA, secretory proteins and transcription mechanisms). In addition, they are relatively easy and cheap to culture under laboratory conditions, display rapid growth, can be easily genetically manipulated and are able to achieve most […]
Monitoring E. coli Cultures with the BioLector and Multisizer 4e Instruments
Escherichia coli (E. coli) is a facultative anaerobic bacterium that lives in the lower intestine of warm-blooded animals, including humans. E. coli can be cultured easily and inexpensively in a laboratory setting and has become an important model organism in genetics, microbiology and biotechnology. E. coli is the most common organism used for the large-scale […]
The importance of Multi-Flow Testing?
Revolution Multi-Flow Test Test Type: Instantaneous Dynamic Measures: Micro-Structure Powders can behave very differently depending on the amount of energy they are subjected to as they move through handling equipment. One powder may flow more evenly as it is subjected to more mechanical energy while another powder may become erratic. This behaviour can be studied […]
4 Applications of Enhanced Laser Diffraction Analysis
Particles diffract light through a specific angle depending upon their size, creating a diffraction pattern of light and dark circles. Measuring the intensity of light over a wide range of angles enables analysts to determine a particle size distribution. Laser diffraction analysis operates on this general principle. Gustav Mie’s theory of diffraction is used in […]
Characterisation of Membranes
Our porometers can be applied to the characterization of polymeric and ceramic membranes for micro and ultrafiltration applications with pore sizes ranging from 500 μm down to 2 nm. Flat sheet, tubular and hollow fibers can be measured by using an appropriate sample holder. Both POROLUX™ series and POROLIQ™ series are suitable for membrane characterization […]
Comparing FlowCam Results with Light Obscuration: A Study by Japan’s National Institute of Health Sciences
In their recent publication, Quantitative Evaluation of Insoluble Particulate Matters in Therapeutic Protein Injections Using Light Obscuration and Flow Imaging Methods, Shibata et. al. compare the ability of Light Obscuration and Flow Imaging to detect and accurately characterize subvisible particles in injectable drugs. The team at Japan’s National Institute of Health Sciences write the following: […]
Binding Interaction Studies Between Heparin and SARS-CoV-2 by Using P4SPR™
Introduction In search of therapeutic treatments that can inhibit the infection of SARS-CoV-2 viruses that cause COVID-19 in humans, heparin, as well as heparan sulphate (HS) and its derivatives, may be potential drug candidates due to their known binding interactions with surface viral proteins [1]. Furthermore, they are inexpensive and widely available. Heparin is a […]