FlowCam Nano is a flow imaging microscope for submicron particle imaging in biopharmaceutical and other materials applications. Its advanced optical imaging capabilities enable detection and morphological analysis of the smallest particles observable using light microscopy.

Detect submicron-sized particles including protein aggregates and small oligomers of drug delivery vehicles like LNPs and exosomes to proactively improve product stability and quality—even before larger particles are present.

• Detect early API aggregate formation and other forms of sample degradation that are prone to generating larger subvisible and visible particles
• Acquire high-resolution images to detect and identify submicron particle types to inform product development and monitor product quality
• Obtain size, morphology, and relative concentrations of particles that are too small to be detected by traditional Flow Imaging Microscopy
• Experience integrated, industry-leading VisualSpreadsheet software with the unique ability to image, classify, and characterize nanoparticles in real-time with an easy-to-use interface

USP <1788> introduces flow imaging as a technique to provide complementary morphology information and to overcome undercounting and undersizing challenges with the light obscuration method when measuring translucent particles such as proteins and other biological drugs.

Obtain light obscuration data to meet USP regulatory guidelines and verify your results with the highest quality images in FlowCam LO – all in a single instrument and single sample run.

• Perform both flow imaging and light obscuration measurements sequentially in the same instrument
• Obtain compendial particle sizing and counting according to USP <787> and <788>
• Acquire statistically significant results in less than a minute, with as little as 100 μL of sample
• Monitor and control particulates in your formulations

FlowCam Macro is the flow imaging microscope of choice for visible particles. Direct, image-based morphological measurements give you details not available with other particle analysis methods.

Monitor the sphericity of manufactured beads, the shape and structure of fibers, polymers, crystals, and powders, or achieve taxonomic identification of zooplankton with superior particle images and image analysis VisualSpreadsheet software.

• Perform automated flow imaging microscopy for visible particle analysis
• Perform quality control of food and beverage ingredients
• Ensure product quality for advanced materials applications
• Measure a broad scope of morphological parameters for cross-validation of data
• Recirculate sample volume to ensure that representative samples are measured