Gene Regulation, Lac Operon / Lac Repressor (DNA-Protein binding)
The regulation of lac operon (lacO), a set of Escherichia Coli genes responsible for the lactose metabolism in the bacteria, by the lac repressor is a well-studied system in molecular biology. The lac repressor, a DNA-binding protein (lacl), is key to controlling the lac operon. The equilibrium dissociate constant (KD) of this system is estimated to be in the nM range.
