Rapid screening of protein-protein interactions
The central dogma of molecular biology stipulates that DNA is transcribed to RNA, and RNA is subsequently translated into protein [1] . While the central dogma adequately encapsulates the field of molecular biology, protein-protein interactions are at the heart of virtually every biological process. While many are familiar with the term genome, the comprehensive genes of organism, or the term proteome, the comprehensive proteins expressed in an organism, fewer are familiar with an organism’s interactome. In short, the interactome typically refers to the entire set of protein-protein interactions (PPIs) in an organism. The importance of protein-protein interactions, and its central nature in biological processes, is highlighted by its role in human diseases.
