Understanding the mechanism of action of transmembrane (TM) proteins
The CD36 (cluster of differentiation 36) is part of transmembrane proteins with versatile functions. Encoded by the CD36 gene, the CD36 protein is found on the surface of many cell types in vertebrates. It has various roles in lipid uptake, cell adhesion and pathogen sensing. As a result, several diseases related to arterial hypertension, diabetes, cardiomyopathy are associated with mutation or misregulation of these transmembrane proteins.
