Investigating the Stability of Ibuprofen using BeScan Lab
Ibuprofen suspension is a widely recognized pain reliever whose active pharmaceutical ingredients are evenly dispersed in the system. Suspension is a thermodynamically unstable system because of its high surface energy, but also a kinetic stable system due to the optimization of the formulation. As time goes on, flocculation, sedimentation, or phase separation may occur in the suspension, which leads to drug deterioration. To ensure the homogenization of the active ingredients, it is recommended to shake the ibuprofen suspension before dosing. Good stability after redispersion is a key to the high effectiveness of ibuprofen, demonstrating even distribution of active ingredients with external force after long-term storage.